Fourier-transform mass spectrometry of large molecules by electrospray ionization.

Characterization of nitrogen compounds in coker gas oil by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry and Fourier transform infrared spectroscopy

In this study, the classes and structures of nitrogen species in coker gas oil (CGO) are characterized by electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) combined with Fourier transform infrared (FT-IR) spectroscopy. The results demonstrate that the m/z of basic and non-basic nitrogen compounds ranges from 180 to 560 and from 200 to 460, res...

Fourier Transform Mass Spectrometry and Nuclear Magnetic Resonance Analysis for the Rapid and Accurate Characterization of Hexacosanoylceramide

Ceramides are a central unit of all sphingolipids which have been identified as sites of biological recognition on cellular membranes mediating cell growth and differentiation. Several glycosphingolipids have been isolated, displaying immunomodulatory and anti-tumor activities. These molecules have generated considerable interest as potential vaccine adjuvants in humans. Accurate analyses of th...

Molecular weight determination of plasmid DNA using electrospray ionization mass spectrometry.

Ionization and molecular weight (MW) determination of megadalton size plasmid DNA has been achieved using electrospray ionization (ESI) with Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. DNA molecules were shown to remain intact through electrospray ionization by collection on a specially prepared surface, followed by agarose gel electrophoresis. Individual highly charged...

Interactive comment on “Molecular characterization of aerosol-derived water soluble organic carbon using ultrahigh resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry” by A. S. Wozniak et al

Analysis of combinatorial libraries using electrospray Fourier transform ion cyclotron resonance mass spectrometry.

Electrospray ionization coupled with Fourier transform ion cyclotron resonance (FTICR) mass spectrometry has been used to provide information about complete combinatorial libraries of small peptides containing 10(3)-10(4) components. The fidelity of attempted synthesis steps can be ascertained rapidly, and, when the extremely high resolution FTICR mass spectra are combined with appropriate comp...